Description

N6-iso-Propyladenosine is a synthetic, modified nucleoside analog of adenosine, where an isopropyl group is substituted at the N6 position of the adenine base. This structural modification is of significant interest in biochemical and pharmaceutical research, particularly for studying adenosine receptor interactions and developing novel therapeutic agents. It serves as a critical intermediate and research tool for scientists in medicinal chemistry, pharmacology, and molecular biology.

Application

• Medicinal Chemistry Research: Key intermediate in the synthesis of novel adenosine receptor (AR) ligands and potential drug candidates targeting neurological, cardiovascular, and inflammatory conditions.
• Biochemical Studies: Used as a tool compound to investigate adenosine receptor subtype selectivity, signaling pathways, and enzyme inhibition mechanisms.
• Pharmaceutical Development: Serves as a building block for the development of prodrugs and nucleotide analogs with enhanced metabolic stability or targeted delivery.
• Academic Research: Employed in university and institutional labs for fundamental studies in nucleoside chemistry, molecular recognition, and structure-activity relationships (SAR).
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in HPLC or LC-MS analysis of related compounds.

Basic Information

Product Name	N6-iso-Propyladenosine
CAS No.	17270-23-4
Molecular Formula	C13H19N5O4
Molecular Weight	309.32 g/mol
Synonyms	N6-(1-Methylethyl)adenosine; N6-Isopropyladenosine; 6-(Isopropylamino)-9-β-D-ribofuranosyl-9H-purine; 6-[(Propan-2-yl)amino]-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purine; Adenosine, N6-(1-methylethyl)-; iso-Pr-Ado
EINECS	Contact for details

Quality Control

Our N6-iso-Propyladenosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.