Description

5'-Deoxy-5'Fluorothymidine is a fluorinated nucleoside analog with significant biochemical and pharmaceutical relevance. This compound serves as a crucial intermediate in the synthesis of more complex antiviral and anticancer agents, offering a versatile building block for targeted drug development. It is primarily utilized by research institutions, pharmaceutical manufacturers, and fine chemical producers engaged in nucleoside chemistry and oncology research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to thymidine metabolism and DNA synthesis pathways.
• Antiviral Agent Development: Serves as a core structure for developing compounds targeting viral polymerases.
• Oncology Research: Investigated for its potential role in creating chemotherapeutic agents that interfere with cancer cell proliferation.
• Radiopharmaceuticals: Potential use as a precursor for fluorine-18 labeled compounds used in Positron Emission Tomography (PET) imaging.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing of specialized nucleoside derivatives.

Basic Information

Product Name	5'-Deoxy-5'Fluorothymidine
CAS No.	17199-43-8
Molecular Formula	C10H13FN2O5
Molecular Weight	260.22 g/mol
Synonyms	5'-Deoxy-5-fluorothymidine; 5-Fluoro-5'-deoxythymidine; 5'-dFdT; FdT; 1-(5-Deoxy-5-fluoro-β-D-ribofuranosyl)thymine; 5-Fluoro-2'-deoxy-5'-thymidine; FTdR; NSC 27640
EINECS	Contact for details

Quality Control

Our 5'-Deoxy-5'Fluorothymidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets high-purity standards suitable for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.