Description

(25S)-5β-Spirostane-1β,3β,5-Triol is a high-purity steroidal sapogenin derivative, a key intermediate in the synthesis of complex bioactive molecules. Its defined stereochemistry and hydroxylation pattern make it a valuable building block for pharmaceutical research and development. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for the development of novel steroid-based therapeutics and reference standards.

Application

• Pharmaceutical Intermediate: A critical chiral precursor for the synthesis of steroidal drugs, including potential anti-inflammatory, hormonal, and cardiovascular agents.
• Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for method development, validation, and quality control of related steroid compounds.
• Biochemical Research: Employed in academic and industrial research to study steroid biosynthesis pathways, enzyme inhibition, and receptor-ligand interactions.
• Fine Chemical Synthesis: Serves as a starting material for the preparation of more complex, functionalized spirostane derivatives with tailored biological activities.

Basic Information

Product Name	(25S)-5β-Spirostane-1β,3β,5-Triol
CAS No.	17149-95-0
Molecular Formula	C27H44O5
Molecular Weight	448.64 g/mol
Synonyms	(25S)-Spirostane-1β,3β,5-triol; 1β,3β,5-Trihydroxy-(25S)-5β-spirostane; (25S)-1β,3β,5-Trihydroxy-5β-spirostan; 5β-Spirostane-1β,3β,5-triol, (25S)-; Tigogenin 1β,3β,5-triol (25S-isomer); (25S)-1β,3β,5-Trihydroxytigogenin
EINECS	Contact for details

Quality Control

Our (25S)-5β-Spirostane-1β,3β,5-Triol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets the stringent requirements for research and synthesis applications. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.