Description

2,3:5,6-Di-o-Isopropylidene-A-D-Manno-Furanosyl Chloride is a protected sugar derivative and a crucial glycosyl donor in synthetic organic chemistry. This compound is valued for its role in the stereoselective construction of complex carbohydrate structures and nucleoside analogs. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of antiviral agents, nucleotide-based therapeutics, and advanced glycoconjugates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of nucleoside analogs with potential antiviral or anticancer activity.
• Carbohydrate Chemistry Research: Essential glycosyl donor for the stereocontrolled synthesis of complex oligosaccharides and glycoconjugates.
• Prodrug Development: Used in creating masked or protected forms of bioactive nucleosides to improve stability and bioavailability.
• Chemical Biology Probes: Serves as a precursor for labeled sugar nucleotides or other tools used to study glycosylation processes.
• Process Chemistry: Employed in scale-up routes for the manufacture of active pharmaceutical ingredients (APIs) requiring specific sugar motifs.

Basic Information

Product Name	2,3:5,6-Di-o-Isopropylidene-A-D-Manno-Furanosyl Chloride
CAS No.	17087-84-2
Molecular Formula	C12H17ClO5
Molecular Weight	276.71 g/mol
Synonyms	1-Chloro-2,3:5,6-di-O-isopropylidene-α-D-mannofuranose; Diacetone Mannose Chloride; 2,3:5,6-Di-O-isopropylidene-α-D-mannofuranosyl chloride; 1-Chloro-1-deoxy-2,3:5,6-di-O-isopropylidene-α-D-mannofuranose; α-D-Mannofuranosyl chloride, 2,3:5,6-di-O-(1-methylethylidene)-; Di-O-isopropylidene-α-D-mannofuranosyl chloride
EINECS	Contact for details

Quality Control

Our 2,3:5,6-Di-o-Isopropylidene-A-D-Manno-Furanosyl Chloride is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. Due to its hygroscopic (moisture-sensitive) nature, containers should be sealed under an inert atmosphere after opening and allowed to reach room temperature before use to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.