Description

5α-Cholestane-3α,7α,12α,25,26-Pentaol is a high-purity, polyhydroxylated sterol derivative. This compound serves as a critical reference standard and synthetic intermediate in advanced biochemical research and pharmaceutical development. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors requiring precise sterol analogs for metabolic studies, drug discovery, and analytical method validation.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of sterol metabolites and related compounds in drug development and quality control laboratories.
• Biochemical Research: Acts as a key intermediate or substrate in the study of enzymatic pathways, particularly those involving cholesterol metabolism and bile acid synthesis.
• Metabolite Synthesis: Serves as a precursor for the synthesis of complex, biologically active sterol derivatives and labeled compounds for tracer studies.
• Analytical Method Development: Employed to develop and validate chromatographic methods (HPLC, LC-MS) for the detection and quantification of sterols in various matrices.
• Academic Research: Utilized in universities and research institutes for fundamental studies in organic chemistry, steroid chemistry, and molecular biology.

Basic Information

Product Name	5α-Cholestane-3α,7α,12α,25,26-Pentaol
CAS No.	16991-60-9
Molecular Formula	C₂₇H₄₈O₅
Molecular Weight	452.67 g/mol
Synonyms	5α-Cholestane-3α,7α,12α,25,26-pentol; 3α,7α,12α,25,26-Pentahydroxy-5α-cholestane; (25R)-5α-Cholestane-3α,7α,12α,25,26-pentaol; 25R-Cholestane-3α,7α,12α,25,26-pentaol; 5α-Cholestanepentaol; 3α,7α,12α,25,26-Pentahydroxycholestane
EINECS	Contact for details

Quality Control

Our 5α-Cholestane-3α,7α,12α,25,26-Pentaol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.