Description

3-β-D-Ribofuranosylpyrrole-2,5-Dione is a specialized nucleoside analogue and a key synthetic intermediate in medicinal chemistry. This compound matters for its role as a versatile building block in the synthesis of novel antiviral and anticancer agents, particularly those targeting RNA viruses and cellular enzymes. Pharmaceutical R&D laboratories and fine chemical manufacturers need it for developing next-generation therapeutics and for use in biochemical research as a modified nucleoside precursor.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel nucleoside-based antiviral and anticancer drugs.
• Biochemical Research: Used as a modified nucleoside analogue in studies of enzyme inhibition, RNA synthesis, and metabolic pathways.
• Antiviral Agent Development: Serves as a building block for creating compounds that target RNA-dependent RNA polymerases of various viruses.
• Proteasome Inhibitor Synthesis: Employed in the research and development of proteasome inhibitors for oncology applications.
• Glycobiology Studies: Utilized in research involving glycosylated heterocycles and their biological interactions.
• Fine Chemical Synthesis: Acts as a chiral starting material for the preparation of complex, high-value specialty chemicals.

Basic Information

Product Name	3-β-D-Ribofuranosylpyrrole-2,5-Dione
CAS No.	16755-07-0
Molecular Formula	C9H11NO6
Molecular Weight	229.19 g/mol
Synonyms	3-β-D-Ribofuranosylpyrrole-2,5-dione; 3-(β-D-Ribofuranosyl)maleimide; 3-(β-D-Ribofuranosyl)-1H-pyrrole-2,5-dione; 3-Ribofuranosylmaleimide; 3-(β-D-Ribofuranosyl)pyrrole-2,5-dione; NSC 154020; 3-(β-D-Ribofuranosyl)-2,5-pyrroledione
EINECS	Contact for details

Quality Control

Our 3-β-D-Ribofuranosylpyrrole-2,5-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.