Description

Androst-5-En-17-One, 3,16-Bis(Acetyloxy)-, (3Beta,16Beta)- is a high-purity steroid derivative, specifically a diacetylated androstane compound, serving as a critical advanced intermediate in pharmaceutical synthesis. Its precise stereochemistry and functionalization make it a valuable building block for the research and development of complex therapeutic agents. This compound is essential for manufacturers and R&D laboratories focused on endocrinology, oncology, and other specialized areas of medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex steroid-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in academic and industrial laboratories for investigating steroid metabolism, receptor binding, and structure-activity relationships (SAR).
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical analysis.
• Biochemical Research: Employed in studies related to hormone biosynthesis pathways and enzyme inhibition assays.
• Process Chemistry: Utilized for scaling up synthetic routes and optimizing production processes for steroid-derived therapeutics.

Basic Information

Product Name	Androst-5-En-17-One, 3,16-Bis(Acetyloxy)-, (3Beta,16Beta)-
CAS No.	16597-57-2
Molecular Formula	C23H32O5
Molecular Weight	388.50 g/mol
Synonyms	3β,16β-Diacetoxyandrost-5-en-17-one; 16β-Acetoxy-DHEA 3-acetate; (3β,16β)-3,16-Bis(acetyloxy)androst-5-en-17-one; 3,16-Di-O-acetylandrost-5-en-17-one; Androst-5-ene-3β,16β-diol-17-one diacetate; 16β-Hydroxy-DHEA diacetate; 3β,16β-Dihydroxyandrost-5-en-17-one diacetate
EINECS	Contact for details

Quality Control

Our Androst-5-En-17-One, 3,16-Bis(Acetyloxy)-, (3Beta,16Beta)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Unknown Impurity	≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.