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2-Methyladenosine CAS NO 16526-56-0


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CAS No.:16526-56-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Methyladenosine is a modified nucleoside derivative of adenosine, featuring a methyl group at the 2-position of the adenine base. This structural modification makes it a valuable biochemical tool and a key intermediate in the synthesis of more complex nucleoside analogs and pharmaceutical agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in nucleotide chemistry, antiviral research, and the development of novel therapeutic compounds. The product is supplied with a focus on high purity and batch-to-batch consistency to meet rigorous research and development standards.

Application

  • Biochemical Research: Used as a standard, substrate, or inhibitor in enzymatic studies involving adenosine deaminase, kinases, and other nucleoside-metabolizing enzymes.
  • Pharmaceutical Intermediate: Serves as a critical building block in the synthetic pathway for novel antiviral and anticancer nucleoside analogs.
  • Nucleotide Chemistry: Employed in organic synthesis to create modified RNA/DNA oligonucleotides for structure-activity relationship (SAR) studies.
  • Metabolic Pathway Studies: Acts as a probe to investigate purine salvage pathways and nucleotide metabolism in cellular systems.
  • Reference Standard: Used as a high-purity analytical standard in HPLC, LC-MS, and NMR for method development and quality control of related compounds.

Basic Information

Product Name 2-Methyladenosine
CAS No. 16526-56-0
Molecular Formula C11H15N5O4
Molecular Weight 281.27 g/mol
Synonyms 2-Methyladenosine; 9-β-D-Ribofuranosyl-2-methyladenine; 2-Methyl-9-β-D-ribofuranosyladenine; 2-MA; N6-Methyladenosine (isomer); 2-Methyl-adenosine; Adenosine, 2-methyl-
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Quality Control

Every batch of 2-Methyladenosine is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with high-purity standards for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC) Conforms
Identification (IR) Conforms
Assay (HPLC) ≥ 98.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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