Description

2-tert-Butylbenzoylchloride is a specialized organic intermediate belonging to the class of benzoyl chlorides, characterized by the presence of a bulky tert-butyl group on the aromatic ring. This structural feature makes it a valuable building block for synthesizing complex molecules where steric hindrance and specific electronic properties are required. It is primarily sought after by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the production of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring sterically hindered benzamide or ester functionalities.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and pesticides, where the tert-butyl group can enhance biological activity and stability.
• Polymer Chemistry: Acts as a monomer or modifying agent in the production of specialty polymers and resins, including liquid crystal polymers and high-performance engineering plastics.
• Organic Synthesis & Research: Essential reagent for introducing the 2-tert-butylbenzoyl moiety in academic and industrial research for novel compound libraries.
• Dye and Pigment Manufacturing: Intermediate in the synthesis of specialized dyes and pigments where the bulky group influences color fastness and solubility.
• Ligand and Catalyst Development: Serves as a starting material for creating sophisticated ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2-tert-Butylbenzoylchloride
CAS No.	16372-51-3
Molecular Formula	C11H13ClO
Molecular Weight	196.67 g/mol
Synonyms	2-(tert-Butyl)benzoyl chloride; o-tert-Butylbenzoyl chloride; Benzoic acid, 2-(1,1-dimethylethyl)-, chloride; 2-tert-Butylbenzoic acid chloride; 2-(1,1-Dimethylethyl)benzoyl chloride; 2-t-Butylbenzoyl chloride; o-t-Butylbenzoyl chloride
EINECS	Contact for details

Quality Control

Our 2-tert-Butylbenzoylchloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee it meets your specific R&D or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic and strong acid/organic solvent nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from heat, open flames, and incompatible materials such as bases, alcohols, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.