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2'-Deoxyguanosine 3',5'-Diphosphate CAS NO 16174-59-7


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CAS No.:16174-59-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2'-Deoxyguanosine 3',5'-Diphosphate is a high-purity nucleotide derivative essential for advanced biochemical research and pharmaceutical development. This compound serves as a critical building block and substrate in enzymatic studies, particularly those involving DNA polymerases and kinases. It is primarily utilized by researchers and manufacturers in the fields of molecular biology, diagnostics, and the development of nucleotide-based therapeutics.

Application

  • Biochemical Research: Used as a substrate for studying enzyme kinetics, specificity, and mechanisms of DNA polymerases, ligases, and kinases.
  • Diagnostic Reagent Synthesis: A key precursor in the manufacturing of labeled nucleotides for PCR, sequencing, and other molecular diagnostic assays.
  • Pharmaceutical Intermediates: Serves as a critical raw material in the synthesis of novel antiviral and anticancer nucleotide analogs.
  • Enzyme Characterization: Employed in high-throughput screening and activity assays to characterize and validate enzymatic targets.
  • Metabolic Pathway Studies: Utilized in research focused on nucleotide metabolism and related cellular processes.

Basic Information

Product Name 2'-Deoxyguanosine 3',5'-Diphosphate
CAS No. 16174-59-7
Molecular Formula C10H15N5O10P2
Molecular Weight 427.20 g/mol
Synonyms dGDP; 2'-Deoxyguanosine-5'-diphosphate; Deoxyguanosine diphosphate; dGuanosine-5'-diphosphate; Deoxyguanylyl phosphate; Guanosine 5'-(trihydrogen diphosphate), 2'-deoxy-; 2'-Deoxy-GDP
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Quality Control

Our 2'-Deoxyguanosine 3',5'-Diphosphate is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant research and development standards, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC) Conforms
Identification (NMR) Conforms
Purity (HPLC) ≥ 95%
Water Content (KF) ≤ 5.0%
Endotoxin < 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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