Description

12-Oxo-9(11)-Dehydroestradiol is a high-purity, synthetic steroid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate and reference standard for the synthesis and analytical study of novel steroidal compounds. It is primarily utilized by research institutions, pharmaceutical companies, and contract development and manufacturing organizations (CDMOs) engaged in endocrinology, oncology, and metabolic disease research. Our supply is characterized by stringent quality control to ensure batch-to-batch consistency for reliable experimental outcomes.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex steroid-based active pharmaceutical ingredients (APIs) and novel drug candidates.
• Reference Standard: Used as a certified reference material (CRM) in analytical methods development and validation for quality control laboratories.
• Biochemical Research: Employed in in vitro studies to investigate steroid hormone metabolism, receptor binding affinity, and enzymatic pathways.
• Academic Research: Serves as a substrate or reagent in university and institutional labs for fundamental studies in organic chemistry and medicinal chemistry.
• Metabolite Standard: Acts as a standard for the identification and quantification of related metabolites in bioanalytical assays (e.g., LC-MS/MS).

Basic Information

Product Name	12-Oxo-9(11)-Dehydroestradiol
CAS No.	16143-51-4
Molecular Formula	C18H22O3
Molecular Weight	286.36 g/mol
Synonyms	9(11)-Dehydro-12-oxoestradiol; Estra-1,3,5(10)-triene-3,17β-diol-12-one; 12-Oxoestra-1,3,5(10),9(11)-tetraene-3,17β-diol; 12-Keto-δ9(11)-estradiol; 12-Oxo-δ9(11)-estradiol; 12-Oxoestradiol-9(11)-ene
EINECS	Contact for details

Quality Control

Every batch of 12-Oxo-9(11)-Dehydroestradiol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to support its use in regulated environments. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as purity (by HPLC), identity confirmation (by IR and MS), and related substance profiles. Our quality commitment ensures material suitable for research and development applications requiring high reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.