Description

3-Alpha,12-α-Diacetoxypregnan-20-One is a high-purity, synthetic pregnane derivative, serving as a critical intermediate in advanced pharmaceutical synthesis. Its specific stereochemistry makes it a valuable building block for the research and development of steroid-based therapeutics. This compound is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel drug candidates, particularly within the fields of endocrinology and metabolic disease.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex steroid-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new therapeutic agents.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Biochemical Research: Employed in studies investigating steroid hormone pathways, receptor binding, and enzymatic transformations.

Basic Information

Product Name	3-Alpha,12-α-Diacetoxypregnan-20-One
CAS No.	15991-93-2
Molecular Formula	C25H38O5
Molecular Weight	418.57 g/mol
Synonyms	3α,12α-Diacetoxypregnan-20-one; 20-Oxo-5β-pregnane-3α,12α-diyl diacetate; Pregnan-20-one, 3,12-diacetoxy-, (3α,5β,12α)-; 5β-Pregnane-3α,12α-diol-20-one 3,12-diacetate
EINECS	Contact for details

Quality Control

Our 3-Alpha,12-α-Diacetoxypregnan-20-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical intermediate use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). The product should be kept under inert conditions if long-term stability is required.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.