Description

2,3'-Anhydrothymidine is a high-purity nucleoside derivative and a key synthetic intermediate in organic chemistry. This compound is of significant value for the research and development of novel antiviral agents and modified oligonucleotides. It is primarily sought after by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions engaged in nucleoside chemistry and medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new therapeutic candidates.
• Oligonucleotide Synthesis: Serves as a modified precursor for creating specialized DNA/RNA sequences with altered properties.
• Biochemical Research: Employed in enzymatic studies and as a substrate analog to investigate metabolic pathways.
• Process Development: Utilized in scaling up and optimizing synthetic routes for complex nucleoside-based Active Pharmaceutical Ingredients (APIs).

Basic Information

Product Name	2,3'-Anhydrothymidine
CAS No.	15981-92-7
Molecular Formula	C10H12N2O4
Molecular Weight	224.21 g/mol
Synonyms	2,3'-Anhydro-1-(2-deoxy-β-D-erythro-pentofuranosyl)thymine; 2,3'-Cyclothymidine; 2,2'-Anhydrothymidine (common misnomer); 1-(2-Deoxy-β-D-erythro-pentofuranosyl)-2,3'-anhydrothymine; Thymidine 2,3'-anhydronucleoside; 2,3'-O-Anhydrothymidine; NSC 112907
EINECS	Contact for details

Quality Control

Our 2,3'-Anhydrothymidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by spectroscopic methods (NMR, IR). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.