Description

2',3',5'-Tri-o-Acetylnebularine is a key acetylated derivative of the nucleoside nebularine, serving as a crucial synthetic intermediate and research chemical. This compound is valued for its role in nucleoside chemistry, enabling the study of enzyme interactions and the synthesis of modified nucleosides with potential biological activity. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for drug discovery and biochemical research.

Application

• Pharmaceutical Intermediate: A vital building block in the synthesis of novel nucleoside analogs and prodrugs for antiviral or anticancer research.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate nucleoside-metabolizing enzymes like kinases and phosphorylases.
• Organic Synthesis: Serves as a protected nucleoside precursor for the preparation of more complex oligonucleotides or labeled compounds.
• Academic Research: Employed in universities and research institutes for fundamental studies in medicinal chemistry and nucleic acid chemistry.
• Reference Standard: Can be used as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	2',3',5'-Tri-o-Acetylnebularine
CAS No.	15981-63-2
Molecular Formula	C₁₅H₁₈N₄O₇
Molecular Weight	366.33 g/mol
Synonyms	9-β-D-Ribofuranosylpurine 2',3',5'-triacetate; Nebularine 2',3',5'-triacetate; 2',3',5'-Tri-O-acetyl-9-β-D-ribofuranosylpurine; 9-(2,3,5-Tri-O-acetyl-β-D-ribofuranosyl)purine; Triacetylnebularine; Purine riboside triacetate; 9-β-D-Ribofuranosylpurine triacetate
EINECS	Contact for details

Quality Control

Our 2',3',5'-Tri-o-Acetylnebularine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by spectroscopic methods, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.