Description

5'-Deoxyuridine is a modified nucleoside derivative of uridine, where the 5'-hydroxyl group is replaced by a hydrogen atom. This structural modification makes it a valuable intermediate and reference standard in the synthesis of more complex nucleoside analogs and pharmaceutical agents. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors. Its role is critical in the development of antiviral and anticancer compounds, as well as in biochemical research.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel antiviral and anticancer nucleoside drugs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving thymidine kinase and other nucleoside-metabolizing enzymes.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Proteomics & Genomics: Employed in research exploring nucleic acid chemistry, DNA/RNA modification, and related metabolic pathways.
• Academic & Industrial R&D: Fundamental material for investigating the structure-activity relationships of nucleoside analogs.

Basic Information

Product Name	5'-Deoxyuridine
CAS No.	15958-99-3
Molecular Formula	C9H12N2O5
Molecular Weight	228.20 g/mol
Synonyms	5'-Deoxyuridine; 1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione; 2'-Deoxyuridine (common misnomer, verify context); Uridine, 5'-deoxy-; 5'-dUrd; 5'-Deoxy-uridine; Deoxyuridine (non-specific).
EINECS	Contact for details

Quality Control

Our 5'-Deoxyuridine is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR, to ensure it meets high-grade specifications suitable for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.