Description

5'-Acetyl-2',3'-Isopropylideneadenosine is a key protected nucleoside derivative, serving as a crucial synthetic intermediate in advanced organic and medicinal chemistry. Its primary value lies in enabling the selective functionalization of the ribose sugar moiety, which is essential for the synthesis of modified nucleotides and nucleoside analogs. This compound is particularly vital for researchers and manufacturers in the pharmaceutical industry developing antiviral and anticancer therapeutics, as well as for biochemical studies exploring nucleotide function.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel nucleoside-based antiviral and anticancer agents.
• Biochemical Research: Used in the study of enzyme mechanisms, particularly those involving adenosine kinases and other nucleotide-processing enzymes.
• Prodrug Development: Serves as a precursor for prodrug strategies aimed at improving the bioavailability and targeting of nucleoside therapeutics.
• Oligonucleotide Synthesis: Employed in the preparation of modified RNA and DNA analogs for diagnostic and therapeutic applications.
• Chemical Biology Probes: Utilized to create labeled or tagged adenosine derivatives for tracking cellular processes.

Basic Information

Product Name	5'-Acetyl-2',3'-Isopropylideneadenosine
CAS No.	15888-38-7
Molecular Formula	C15H19N5O5
Molecular Weight	349.34 g/mol
Synonyms	2',3'-O-Isopropylideneadenosine 5'-acetate; 5'-O-Acetyl-2',3'-O-isopropylideneadenosine; N6-Adenosine, 2',3'-O-(1-methylethylidene)-, 5'-acetate; 1-(5-O-Acetyl-2,3-O-isopropylidene-β-D-ribofuranosyl)adenine; 5'-Acetyl-2',3'-O-isopropylideneadenosine; Protected Adenosine Derivative
EINECS	Contact for details

Quality Control

Our 5'-Acetyl-2',3'-Isopropylideneadenosine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR), to ensure it meets the high standards required for research and pharmaceutical synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.