Description

(E)-3-o-Tolyl-Acryloyl Chloride is a versatile and highly reactive acid chloride intermediate essential for organic synthesis. Its core value lies in enabling the efficient introduction of the (E)-3-o-tolylacryloyl moiety into target molecules, facilitating the creation of complex chemical architectures. This compound is particularly valuable for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a critical building block for active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds requiring the (E)-cinnamoyl structural motif.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators.
• Material Science Precursor: Employed in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Peptide & Protein Modification: Acts as an acylating agent for modifying amino acids, peptides, or proteins to alter their properties.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating novel chemical entities.
• Dye & Pigment Manufacturing: Serves as an intermediate in the synthesis of complex organic dyes and high-performance pigments.

Basic Information

Product Name	(E)-3-o-Tolyl-Acryloyl Chloride
CAS No.	15873-40-2
Molecular Formula	C10H9ClO
Molecular Weight	180.63 g/mol
Synonyms	(E)-3-(2-Methylphenyl)acryloyl chloride; (E)-3-(o-Tolyl)acryloyl chloride; trans-3-(2-Methylphenyl)propenoyl chloride; 2-Methylcinnamoyl chloride; (E)-2-Methylcinnamoyl chloride; (E)-3-(2-Methylphenyl)-2-propenoyl chloride; (E)-3-(o-Tolyl)prop-2-enoyl chloride
EINECS	Contact for details

Quality Control

Our (E)-3-o-Tolyl-Acryloyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from strong bases, oxidizers, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.