Description

2-Bromoestradiol,(13S,17S)-2-Bromo-13-Methyl-7,8,9,11,12,13,14,15,16,17-Decahydro-6H-Cyclopenta[A]Phenanthrene-3,17-Diol CAS NO 15833-07-5 is a brominated derivative of estradiol, a key steroid hormone. This compound is valued as a crucial biochemical tool and synthetic intermediate for advanced research and pharmaceutical development. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in endocrinology, steroid chemistry, and novel therapeutic agent synthesis.

Application

• Biochemical Research: Used as a reference standard and probe in studies of estrogen receptor (ER) binding, function, and signaling pathways.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of more complex steroid-based drug candidates and labeled compounds.
• Endocrinology Studies: Employed to investigate the structure-activity relationships (SAR) of estrogen analogs and their metabolic pathways.
• Academic Research: Utilized in university and institutional labs for teaching and advanced research in organic and medicinal chemistry.
• Diagnostic Development: Acts as a precursor or competitor in the development of assays and diagnostic kits related to hormonal analysis.

Basic Information

Item	Details
Product Name	2-Bromoestradiol,(13S,17S)-2-Bromo-13-Methyl-7,8,9,11,12,13,14,15,16,17-Decahydro-6H-Cyclopenta[A]Phenanthrene-3,17-Diol
CAS No.	15833-07-5
Molecular Formula	C18H25BrO2
Molecular Weight	353.30 g/mol
Synonyms	2-Bromoestradiol; 2-Bromo-17β-estradiol; (13S,17S)-2-Bromo-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol; 2-Bromo-E2; 2-Br-Estradiol; Estra-1,3,5(10)-triene-3,17β-diol, 2-bromo-; 17β-Estradiol 2-bromo derivative
EINECS	Contact for details

Quality Control

Our 2-Bromoestradiol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC and NMR, to ensure high purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0% (on dried basis)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.