Description

Vidarabine 2',3',5'-Triacetate is a chemically modified nucleoside analog, specifically the triacetylated derivative of the antiviral agent vidarabine. This intermediate is of significant value in pharmaceutical synthesis, offering enhanced stability and solubility properties for further chemical processing. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development and production of antiviral and anticancer therapeutics.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the production of antiviral nucleoside analogs.
• Antiviral Drug Research: Used in the research and development of new therapeutic agents targeting herpesviruses and other DNA viruses.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies related to nucleic acid metabolism.
• Prodrug Development: The acetyl groups act as protecting groups, making it a valuable intermediate for prodrug synthesis to improve drug delivery and bioavailability.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Vidarabine 2',3',5'-Triacetate
CAS No.	15830-52-1
Molecular Formula	C18H21N5O8
Molecular Weight	435.39 g/mol
Synonyms	9-β-D-Arabinofuranosyladenine 2',3',5'-Triacetate; Ara-A Triacetate; Adenine Arabinoside Triacetate; 2',3',5'-Tri-O-acetylvidarabine; Vidarabine Triacetate; 9-(2,3,5-Tri-O-acetyl-β-D-arabinofuranosyl)adenine; Vira-A Triacetate
EINECS	Contact for details

Quality Control

Our Vidarabine 2',3',5'-Triacetate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets exacting standards for pharmaceutical intermediate applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.