Description

4-Pregnene-3-Alpha,20-α-Diol is a key steroid intermediate and reference standard of significant importance in pharmaceutical research and development. This compound is valued for its role in the synthesis and analytical characterization of more complex steroid hormones and their metabolites. It is primarily needed by research institutions, pharmaceutical manufacturers, and analytical laboratories engaged in steroid chemistry, drug discovery, and quality control processes.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of more complex steroid-based active pharmaceutical ingredients (APIs).
• Analytical Reference Standard: Used for method development, calibration, and quantification in chromatographic analyses (HPLC, GC) and spectroscopy to ensure product purity and identity.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies to investigate steroid metabolism pathways and receptor interactions.
• Metabolite Standard: Employed as an authentic standard for the identification and study of endogenous steroid metabolites in clinical and diagnostic research.
• Process Development: Used in scaling up and optimizing synthetic routes for steroid production within pilot plants and manufacturing facilities.
• Quality Control (QC) Testing: Essential for the identity and purity testing of raw materials and finished steroid products in compliance with pharmacopeial standards.

Basic Information

Product Name	4-Pregnene-3-Alpha,20-α-Diol
CAS No.	15780-16-2
Molecular Formula	C21H34O2
Molecular Weight	318.50 g/mol
Synonyms	3α,20α-Dihydroxypregn-4-ene; 3α,20α-Dihydroxy-4-pregnene; 20α-Hydroxy-4-pregnen-3α-ol; Pregn-4-ene-3α,20α-diol; 3α,20α-Dihydroxy-δ4-pregnene; 3α,20α-Dihydroxypregn-4-ene; 4-Pregnene-3α,20α-diol
EINECS	Contact for details

Quality Control

Our 4-Pregnene-3-Alpha,20-α-Diol is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chromatographic purity assays and spectroscopic identification, to ensure it meets the high standards required for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing specific results for identity, purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.