Description

n-Allyladenosine is a chemically modified nucleoside analog, specifically an allyl-substituted derivative of adenosine. This compound is a crucial building block and research chemical in medicinal chemistry and biochemistry, valued for its role in probing enzyme mechanisms and developing novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on nucleoside-based drug discovery and biochemical tool development.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of novel adenosine receptor modulators and antiviral/anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate the activity and specificity of nucleoside kinases, phosphorylases, and other adenosine-metabolizing enzymes.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to explore the impact of allyl modification on receptor binding affinity and metabolic stability.
• Probe Development: Acts as a starting material for synthesizing affinity probes or fluorescently tagged nucleotides for cellular imaging and proteomics.
• Process Chemistry: Used in scale-up synthesis and process optimization for the production of more complex nucleoside derivatives under GMP or non-GMP conditions.

Basic Information

Product Name	n-Allyladenosine
CAS No.	15763-12-9
Molecular Formula	C₁₃H₁₇N₅O₄
Molecular Weight	307.31 g/mol
Synonyms	9-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-(prop-2-en-1-ylamino)purine; 6-(Allylamino)-9-β-D-ribofuranosyl-9H-purine; Allyladenosine; 6-N-Allyladenosine; Adenosine, N-allyl-; N6-Allyladenosine
EINECS	Contact for details

Quality Control

Our n-Allyladenosine CAS NO 15763-12-9 is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent controls for residual solvents and impurities. We provide Certificates of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or development specifications. Our quality systems support delivery for research, pilot-scale, and non-GMP commercial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.