Description

1-Methyladenosine is a modified nucleoside derivative of adenosine, where a methyl group is attached to the N1 position of the adenine base. This specific modification makes it a valuable biochemical tool and a key intermediate in the study of RNA methylation and epigenetic regulation. It is primarily utilized in advanced life science research, pharmaceutical development, and as a reference standard. Our supply of 1-Methyladenosine CAS NO 15763-06-1 is characterized by high purity and batch-to-batch consistency, meeting the stringent requirements of modern laboratories and production facilities.

Application

• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to RNA modification, particularly for methyltransferase assays.
• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method development in drug discovery.
• Epigenetics & Molecular Biology: A critical compound for investigating the role of N1-methyladenosine (m1A) in tRNA, mRNA, and its impact on gene expression.
• Nucleoside Analog Synthesis: Acts as a key building block for the synthesis of more complex nucleoside analogs with potential therapeutic activity.
• Diagnostic Kit Development: Employed in the formulation of reagents and calibrators for diagnostic assays targeting nucleic acid modifications.

Basic Information

Product Name	1-Methyladenosine
CAS No.	15763-06-1
Molecular Formula	C11H15N5O4
Molecular Weight	281.27 g/mol
Synonyms	N1-Methyladenosine; 1-Methyladenosine; m1A; Adenosine, 1-methyl-; 9-β-D-Ribofuranosyl-1-methyladenine; 1-Methyl-9-β-D-ribofuranosyladenine; NSC 146802
EINECS	Contact for details

Quality Control

Every batch of our 1-Methyladenosine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA), including results for identity, purity, and related substances by HPLC, is supplied with each shipment. Our quality protocols are designed to support compliance with cGMP and ISO 9001 standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.