Description

2'-(5''-Phosphoribosyl)-5'-Adenosine Monophosphate is a specialized nucleotide derivative, a key intermediate in the biosynthesis of coenzymes and other biologically active molecules. This compound is critical for research and development in enzymology and metabolic pathway studies, offering high purity and reliable performance for sensitive biochemical applications. It is essential for pharmaceutical researchers, diagnostic kit manufacturers, and academic institutions focused on nucleotide metabolism and enzyme mechanism elucidation.

Application

• Biochemical Research: Used as a substrate or intermediate in enzymatic studies, particularly those involving NAD(P)+ biosynthesis and salvage pathways.
• Pharmaceutical Development: Serves as a key building block or reference standard in the research of novel therapeutics targeting nucleotide metabolism.
• Diagnostic Reagent Manufacturing: Employed in the formulation of high-sensitivity assay kits for measuring specific enzyme activities or metabolic markers.
• Enzyme Characterization: Acts as a critical reagent for kinetic studies and inhibition profiling of enzymes like nicotinamide mononucleotide adenylyltransferases (NMNATs).
• Metabolomics Studies: Used as an analytical standard in LC-MS or HPLC methods for the quantification of nucleotide-related metabolites in biological samples.
• Cofactor Synthesis: A precursor in the chemical or enzymatic synthesis of complex coenzymes and labeled nucleotide analogs for tracer studies.

Basic Information

Product Name	2'-(5''-Phosphoribosyl)-5'-Adenosine Monophosphate
CAS No.	15720-01-1
Molecular Formula	C15H22N5O14P2
Molecular Weight	565.31 g/mol
Synonyms	PR-AMP; 2'-(5''-Phospho-D-ribosyl)-5'-adenosine monophosphate; 2'-(5''-Phosphoribosyl)-5'-AMP; 5'-Adenylic acid, 2'-(5''-phosphoribosyl)-; NMN-adenylate; Nicotinamide mononucleotide adenylate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 2'-(5''-Phosphoribosyl)-5'-Adenosine Monophosphate is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the exacting standards required for research and development. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to minimize moisture uptake. For prolonged storage under inert atmosphere, contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/UV)	Conforms
Purity (HPLC)	≥ 95%
Assay	≥ 90% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.