Description

Guanosine 2':3'-Cyclic Monophosphate Sodium Salt is a high-purity nucleotide derivative essential for biochemical research and pharmaceutical development. This compound serves as a critical tool for studying cyclic nucleotide signaling pathways and enzyme mechanisms, particularly those involving ribonucleases and phosphodiesterases. It is primarily utilized by research institutions, diagnostic kit manufacturers, and pharmaceutical companies engaged in nucleotide-based drug discovery and molecular biology applications.

Application

• Biochemical Research: Used as a substrate or standard in enzymatic assays to study ribonuclease (RNase) activity, phosphodiesterase function, and nucleotide metabolism.
• Pharmaceutical Development: Serves as a key intermediate or reference compound in the research and synthesis of novel nucleotide-based therapeutics and prodrugs.
• Diagnostic Reagents: Incorporated into enzymatic test kits and calibration standards for clinical diagnostics and life science research tools.
• Cell Signaling Studies: Employed in laboratory investigations of intracellular signaling cascades involving cyclic nucleotides as second messengers.
• Enzyme Kinetics: Acts as a specific substrate for kinetic analysis and inhibition studies of enzymes that interact with cyclic phosphate structures.
• Academic Research: Fundamental tool in university and institutional labs for teaching and advanced research in biochemistry, molecular biology, and enzymology.

Basic Information

Product Name	Guanosine 2':3'-Cyclic Monophosphate Sodium Salt
CAS No.	15718-49-7
Molecular Formula	C10H11N5NaO7P
Molecular Weight	367.19 g/mol
Synonyms	2',3'-cGMP Sodium Salt; Guanosine 2',3'-cyclic monophosphate sodium salt; cGMP (2':3') sodium; Sodium Guanosine-2',3'-cyclophosphate; 9-β-D-Ribofuranosylguanine 2',3'-(hydrogen phosphate) sodium salt; GMP 2',3'-cyclic sodium salt; 2',3'-Cyclic GMP sodium salt; Guanosine 2',3'-cyclic phosphate sodium salt
EINECS	Contact for details

Quality Control

Our Guanosine 2':3'-Cyclic Monophosphate Sodium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and stringent tests for identity, moisture content, and residual solvents. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research-grade and cGMP standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider desiccant and under inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
pH (1% Solution)	6.0 - 8.0
Heavy Metals	≤ 20 ppm
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.