Description

S-Methyl-5'-Methylthioadenosine is a modified nucleoside derivative of significant interest in biochemical research and pharmaceutical development. This compound serves as a key intermediate and reference standard in the study of cellular methylation processes and polyamine biosynthesis. It is primarily utilized by research institutions, pharmaceutical R&D departments, and diagnostic manufacturers. Its role is critical for advancing studies in enzymology, metabolic pathway analysis, and the development of novel therapeutic agents.

Application

• Biochemical Research: Used as a substrate or inhibitor in enzymatic assays, particularly for methyltransferase and polyamine metabolism studies.
• Pharmaceutical R&D: Serves as a critical intermediate or reference standard in the development of drugs targeting cancer, viral infections, and metabolic disorders.
• Diagnostic Reagent Manufacturing: Employed in the production of high-purity reagents and kits for clinical diagnostics and life science research.
• Metabolomics & Proteomics: Acts as a quantitative standard in mass spectrometry for the accurate measurement of related metabolites in biological samples.
• Academic Research: Fundamental tool for investigating S-adenosylmethionine (SAM) cycle and related biochemical pathways in universities and research labs.

Basic Information

Product Name	S-Methyl-5'-Methylthioadenosine
CAS No.	15648-76-7
Molecular Formula	C12H17N5O4S
Molecular Weight	327.36 g/mol
Synonyms	5'-Deoxy-5'-(methylthio)adenosine; 5'-S-Methyl-5'-thioadenosine; 5'-Methylthioadenosine; MTA; S-Methyl-5'-thioadenosine; 5'-Deoxy-5'-(methylthio)adenosine; 5'-(Methylthio)adenosine
EINECS	Contact for details

Quality Control

Our S-Methyl-5'-Methylthioadenosine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider desiccant and under inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.