Description

B-D-Ribofuranuronic Acid,1-(2-Amino-1,6-Dihydro-6-Oxo-9H-Purin-9-Yl)-1-Deoxy- is a high-purity nucleoside derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block and intermediate for the synthesis of novel therapeutic agents, particularly in the fields of antiviral and anticancer drug discovery. It is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of nucleotide-based therapies and prodrugs.

Application

• Pharmaceutical Intermediate: Key synthetic precursor for the development of nucleoside analog drugs targeting viral infections and cancer.
• Antiviral Drug Research: Used in the R&D of novel antiviral compounds, leveraging its modified ribose and purine base structure.
• Oncology Research: Serves as a building block for creating potential chemotherapeutic agents that interfere with DNA/RNA synthesis in cancer cells.
• Prodrug Synthesis: Utilized in designing prodrugs to improve the bioavailability and targeting of active pharmaceutical ingredients (APIs).
• Biochemical Research: Employed in enzymatic studies and as a substrate or inhibitor in studies of nucleoside-metabolizing enzymes.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	B-D-Ribofuranuronic Acid,1-(2-Amino-1,6-Dihydro-6-Oxo-9H-Purin-9-Yl)-1-Deoxy-
CAS No.	15596-14-2
Molecular Formula	C₁₀H₁₁N₅O₆
Molecular Weight	297.23 g/mol
Synonyms	9-(1-Deoxy-β-D-ribofuranuronosyl)guanine; 9-(1-Deoxy-β-D-ribofuranuronosyl)-9H-guanine; 1-Deoxy-1-(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)-β-D-ribofuranuronic acid; β-D-Ribofuranuronic acid, 1-(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)-1-deoxy-; 9-(1-Deoxy-β-D-ribofuranosyluronic acid)guanine; Guanine β-D-ribofuranuronoside; 9-β-D-Ribofuranuronosylguanine
EINECS	Contact for details

Quality Control

Every batch of our nucleoside intermediates is produced under strict quality management systems. We employ advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.