Description

3-Methoxy-7α-Methyl-Estra-2,5(10)-Dien-17β-Ol is a high-purity steroid derivative and a key synthetic intermediate in advanced pharmaceutical research and development. This compound is valued for its specific structural modifications, which make it a crucial building block for creating novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers focused on endocrinology, oncology, and the development of hormone-based therapies.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel steroidal drugs and active pharmaceutical ingredients (APIs).
• Research & Development: Used in academic and industrial laboratories for pharmacological studies and structure-activity relationship (SAR) investigations.
• Hormone Analog Development: Serves as a starting material for creating modified estrogen analogs with targeted biological activity.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Biochemical Tool Compound: Utilized in life science research to study steroid receptor interactions and signaling pathways.

Basic Information

Product Name	3-Methoxy-7α-Methyl-Estra-2,5(10)-Dien-17β-Ol
CAS No.	15506-02-2
Molecular Formula	C₂₀H₂₈O₂
Molecular Weight	300.44 g/mol
Synonyms	7α-Methyl-3-methoxyestra-2,5(10)-dien-17β-ol; 3-Methoxy-7α-methylestra-2,5(10)-dien-17β-ol; 17β-Hydroxy-3-methoxy-7α-methylestra-2,5(10)-diene; 7α-Methyl-3-methoxy-19-nor-17β-pregna-2,5(10)-dien-20-yn-17-ol (related nomenclature); Tibolone intermediate; Livial intermediate; Steroid derivative intermediate
EINECS	Contact for details

Quality Control

Our 3-Methoxy-7α-Methyl-Estra-2,5(10)-Dien-17β-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) documenting all critical quality attributes are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.