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3β-[(3-o-Methyl-6-Deoxy-β-D-Glucopyranosyl)Oxy]-5,14-Dihydroxy-19-Oxo-5β-Card-20(22)-Enolide CAS NO 15487-11-3


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CAS No.:15487-11-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3β-[(3-o-Methyl-6-Deoxy-β-D-Glucopyranosyl)Oxy]-5,14-Dihydroxy-19-Oxo-5β-Card-20(22)-Enolide is a high-purity cardiac glycoside derivative, a critical intermediate in advanced pharmaceutical synthesis. This compound matters for its role as a key building block in the development and production of specialized cardiovascular and other therapeutic agents. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on producing high-value active pharmaceutical ingredients (APIs) and reference standards.

Application

  • Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel cardiac glycoside-based therapeutics.
  • Research & Development: Used as a reference standard and building block in medicinal chemistry for studying structure-activity relationships (SAR).
  • Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the controlled production of specialized cardiovascular drugs.
  • Biochemical Research: Utilized in studies investigating sodium-potassium ATPase inhibition and related cellular mechanisms.
  • Analytical Standard: Provides a high-purity benchmark for quality control and analytical method development (e.g., HPLC, LC-MS).

Basic Information

Product Name 3β-[(3-o-Methyl-6-Deoxy-β-D-Glucopyranosyl)Oxy]-5,14-Dihydroxy-19-Oxo-5β-Card-20(22)-Enolide
CAS No. 15487-11-3
Molecular Formula C30H44O10
Molecular Weight 564.67 g/mol
Synonyms 3-O-Methyl-6-deoxy-β-D-glucopyranosyl gitoxigenin; 3β-[(3-O-Methyl-6-deoxy-β-D-glucopyranosyl)oxy]-5,14-dihydroxy-19-oxo-5β,14β-card-20(22)-enolide; 3-O-Methyl-6-deoxyglucosylgitoxigenin; Gitoxigenin 3-O-methyl-6-deoxy-β-D-glucoside; 3β-[(3-O-Methyl-6-deoxy-β-D-glucopyranosyl)oxy]-14-hydroxy-5β-card-20(22)-enolide-19-one
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Quality Control

Our 3β-[(3-o-Methyl-6-Deoxy-β-D-Glucopyranosyl)Oxy]-5,14-Dihydroxy-19-Oxo-5β-Card-20(22)-Enolide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Loss on Drying ≤ 1.0%
Residue on Ignition ≤ 0.1%
Single Unknown Impurity (HPLC) ≤ 0.5%
Total Impurities (HPLC) ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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