Description

3-Bromopropionyl Chloride is a versatile and highly reactive organic acid chloride derivative. This compound serves as a critical bifunctional building block in organic synthesis, enabling the introduction of both bromoalkyl and acyl chloride functionalities. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to synthesize complex molecules, active pharmaceutical ingredients (APIs), and advanced intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of various drug candidates and active pharmaceutical ingredients (APIs), particularly in the development of protease inhibitors and other biologically active molecules.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators, where its reactive groups allow for the construction of specific bioactive scaffolds.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for the modification of polymers, introducing reactive sites for further functionalization or creating specialty resins.
• Peptide & Protein Modification: Employed as an acylating agent to modify amino acid side chains, such as lysine residues, for biochemical research and bioconjugation applications.
• Ligand & Catalyst Preparation: Useful in the synthesis of specialized ligands for metal complexes and catalysts used in asymmetric synthesis and other advanced chemical transformations.
• Material Science Research: Applied in surface functionalization and the creation of novel organic-inorganic hybrid materials with tailored properties.

Basic Information

Product Name	3-Bromopropionyl Chloride
CAS No.	15486-96-1
Molecular Formula	C3H4BrClO
Molecular Weight	171.42 g/mol
Synonyms	3-Bromopropanoyl Chloride; β-Bromopropionyl Chloride; Bromopropionyl Chloride; 3-Bromopropionic Acid Chloride; NSC 9375; 1-Bromo-3-chloroformylpropane; 3-Bromo-1-chloro-1-oxopropane
EINECS	239-499-9

Quality Control

Our 3-Bromopropionyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including assay, purity profiling, and impurity identification, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. We adhere to cGMP principles where applicable to ensure batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at temperatures between 2°C and 8°C (refrigerated). Due to its highly volatile and hygroscopic nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%
Density (at 20°C)	~1.7 g/mL
Boiling Point	~75-80°C at 20 mmHg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.