Description

3,4-Dihydroxy-5-(6-Oxo-3H-Purin-9-Yl)Oxolane-2-Carboxylic Acid is a high-purity nucleoside derivative with significant biochemical relevance. This compound is valued for its role as a key intermediate in the synthesis of modified nucleotides and for its utility in advanced pharmaceutical research. It is primarily sought by manufacturers and research institutions in the pharmaceutical, biotechnology, and life science sectors for developing novel therapeutics and diagnostic agents.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to nucleotide metabolism and DNA/RNA synthesis.
• Pro-drug Development: Serves as a precursor in the design of pro-drugs to enhance bioavailability and targeting.
• Diagnostic Reagent Manufacturing: Employed in the production of labeled nucleotides for diagnostic assays and sequencing.
• Academic & Contract Research: Essential for fundamental research in medicinal chemistry and molecular biology.
• Reference Standard: Used as a high-purity analytical standard for quality control and method validation in regulatory filings.

Basic Information

Product Name	3,4-Dihydroxy-5-(6-Oxo-3H-Purin-9-Yl)Oxolane-2-Carboxylic Acid
CAS No.	15475-13-5
Molecular Formula	C10H10N4O7
Molecular Weight	298.21 g/mol
Synonyms	9-(2-Carboxy-4,5-dihydroxy-tetrahydrofuran-2-yl)-9H-purin-6-ol; 6-Hydroxy-9-(2-C-carboxy-4,5-dihydroxy-tetrahydrofuran-2-yl)purine; 6-Oxopurine Ribonucleoside-2',3',5'-Tricarboxylic Acid Derivative; 9-(2-Carboxy-4,5-dihydroxytetrahydrofuran-2-yl)hypoxanthine; Acyclovir Carboxylic Acid Analog; Nucleoside Carboxylic Acid Intermediate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 3,4-Dihydroxy-5-(6-Oxo-3H-Purin-9-Yl)Oxolane-2-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP and ISO 9001 standards to support our customers' regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.