Description

3β-[(3-o-Methyl-6-Deoxy-β-D-Glucopyranosyl)Oxy]-5,14,19-Trihydroxy-5β-Card-20(22)-Enolide is a high-purity cardiac glycoside derivative, a compound class known for its potent biological activity. This specialized intermediate is critical for pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents targeting cardiovascular functions. It is essential for R&D chemists and manufacturers in the pharmaceutical and biotechnology sectors requiring precise, high-quality building blocks for complex molecular synthesis.

Application

• Pharmaceutical Intermediate: A key starting material or intermediate in the synthesis of advanced cardiac glycoside-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or probe compound in pharmacological studies to investigate sodium-potassium ATPase (Na+/K+-ATPase) inhibition and related cardiac mechanisms.
• Medicinal Chemistry: Serves as a core scaffold for the design and development of new drug candidates with potential cardiotonic or anticancer properties.
• Analytical Standard: Employed as a certified reference material (CRM) in quality control laboratories for HPLC, LC-MS, or other analytical method development and validation.
• Preclinical Development: Utilized in the formulation of compounds for in vitro and in vivo efficacy and toxicity testing during early-stage drug discovery.

Basic Information

Product Name	3β-[(3-o-Methyl-6-Deoxy-β-D-Glucopyranosyl)Oxy]-5,14,19-Trihydroxy-5β-Card-20(22)-Enolide
CAS No.	15465-83-5
Molecular Formula	C30H46O10
Molecular Weight	566.69 g/mol
Synonyms	3β-[(3-O-Methyl-6-deoxy-β-D-glucopyranosyl)oxy]-5,14,19-trihydroxy-5β-card-20(22)-enolide; 3-O-Methyl-6-deoxy-β-D-glucopyranosyl gitoxigenin; Gitoxigenin 3-O-methyl-6-deoxy-β-D-glucopyranoside; 3β-[(3-O-Methyl-6-deoxy-β-D-glucopyranosyl)oxy]-14,19-dihydroxy-5β-card-20(22)-enolide; 3-O-Methyl-6-deoxyglucogitoxigenin; Methyl-6-deoxyglucogitoxigenin; A derivative of Gitoxigenin
EINECS	Contact for details

Quality Control

Our 3β-[(3-o-Methyl-6-Deoxy-β-D-Glucopyranosyl)Oxy]-5,14,19-Trihydroxy-5β-Card-20(22)-Enolide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.