Description

Cholesterol n-Amyl Carbonate is a high-purity, synthetic derivative of cholesterol, where the hydroxyl group is esterified with n-amyl carbonic acid. This chemical modification enhances its lipophilicity and stability, making it a valuable intermediate for advanced research and specialty chemical synthesis. It is primarily utilized in the pharmaceutical and life science sectors for developing novel drug delivery systems, lipid-based formulations, and as a reference standard in analytical chemistry. Cholesterol n-Amyl Carbonate CAS NO 15455-79-5 offers researchers a reliable building block with defined structure and purity for critical applications.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel steroidal drugs and prodrugs, particularly for targeted delivery applications.
• Lipid Nanoparticle (LNP) Formulation: Used as a structural lipid component in the development of advanced LNPs for mRNA and gene therapy delivery systems.
• Biomimetic Membrane Research: Employed in the study of membrane fluidity, permeability, and cholesterol dynamics within artificial lipid bilayers and vesicles.
• Reference Standard: Acts as a high-purity analytical standard for method development, validation, and quality control in chromatographic analyses (HPLC, GC).
• Cosmetic & Dermatological Actives: Incorporated into high-end cosmetic formulations for its potential skin-barrier enhancing and stabilizing properties.
• Chemical Biology Probes: Utilized to create tagged or modified cholesterol analogs for tracking metabolic pathways and cellular uptake studies.

Basic Information

Product Name	Cholesterol n-Amyl Carbonate
CAS No.	15455-79-5
Molecular Formula	C33H56O3
Molecular Weight	500.80 g/mol
Synonyms	Cholest-5-en-3β-ol 3-n-Amyl Carbonate; 3β-[(Pentyloxy)carbonyloxy]cholest-5-ene; Cholesterol pentyl carbonate; 5-Cholesten-3β-ol, 3-pentyl carbonate; Cholesteryl n-pentyl carbonate; NSC 88812; Cholesterol amyl carbonate
EINECS	Contact for details

Quality Control

Our Cholesterol n-Amyl Carbonate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation by FT-IR and NMR, purity assessment by HPLC, and control of specific impurities. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive (store away from light) and should be handled under inert atmosphere when appropriate to prevent degradation. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.