Description

O2,5'-Anhydrothymidine CAS NO 15425-09-9 is a chemically modified nucleoside derivative, serving as a crucial synthetic intermediate and building block in advanced organic chemistry. Its unique anhydro structure makes it a valuable precursor for the synthesis of novel antiviral agents, modified oligonucleotides, and other bioactive compounds. This high-purity intermediate is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical producers focused on nucleoside chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel antiviral and anticancer nucleoside analogs.
• Oligonucleotide Synthesis: Used in the research and development of modified DNA/RNA strands for therapeutic and diagnostic applications.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies related to nucleotide metabolism.
• Prodrug Development: A precursor in creating prodrug forms of nucleoside-based active pharmaceutical ingredients (APIs).
• Fine Chemical Synthesis: Intermediate for the preparation of complex, high-value specialty chemicals in advanced organic synthesis.
• Academic & Industrial R&D: Fundamental material for exploring new chemical entities and structure-activity relationships in medicinal chemistry.

Basic Information

Product Name	O2,5'-Anhydrothymidine
CAS No.	15425-09-9
Molecular Formula	C10H12N2O4
Molecular Weight	224.21 g/mol
Synonyms	2,5'-Anhydrothymidine; 1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione; Thymidine, 2,5'-anhydro-; 2,2'-Anhydrothymidine; 5'-Deoxy-2,5'-epoxythymidine; NSC 143491; 2,5'-O-Anhydrothymidine
EINECS	Contact for details

Quality Control

Our O2,5'-Anhydrothymidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We are committed to providing material that meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep the container tightly sealed in a desiccator after opening.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.