Description

2-(Hydroxymethyl)-5-(6-Methylsulfanylpurin-9-Yl)Oxolane-3,4-Diol is a modified nucleoside derivative, a key intermediate in the synthesis of specialized oligonucleotides and nucleotide analogs. This compound matters for its role in developing advanced research tools and potential therapeutic agents that target specific genetic pathways. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions focused on nucleic acid chemistry, antiviral drug discovery, and molecular biology.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel nucleoside-based antiviral and anticancer prodrugs.
• Oligonucleotide Synthesis: Used in the preparation of modified DNA/RNA strands for research, diagnostics, and therapeutic applications (e.g., antisense oligonucleotides, siRNA).
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies involving nucleoside kinases, polymerases, and other nucleic acid-metabolizing enzymes.
• Proteomics & Genomics: Employed in the development of probes and tools for studying gene expression, protein-nucleic acid interactions, and cellular signaling pathways.
• Reference Standard: Used as a high-purity certified reference material (CRM) for analytical method development and quality control in pharmaceutical manufacturing.

Basic Information

Product Name	2-(Hydroxymethyl)-5-(6-Methylsulfanylpurin-9-Yl)Oxolane-3,4-Diol
CAS No.	15397-51-0
Molecular Formula	C11H14N4O4S
Molecular Weight	298.32 g/mol
Synonyms	6-Methylmercaptopurine Riboside; 6-Methylthioinosine; 6-Methylthio-9-β-D-ribofuranosylpurine; 6-MMPR; NSC-40774; 6-(Methylthio)-9-β-D-ribofuranosyl-9H-purine; 9-β-D-Ribofuranosyl-6-(methylthio)purine; 6-Methylmercapto-9-β-D-ribofuranosylpurine
EINECS	Contact for details

Quality Control

Our 2-(Hydroxymethyl)-5-(6-Methylsulfanylpurin-9-Yl)Oxolane-3,4-Diol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure compliance with research and pharmaceutical intermediate standards. Certificates of Analysis (COA) with detailed chromatographic data are available for every lot.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.