Description

2-Fluoro-3'-Deoxyadenosine is a fluorinated nucleoside analog of significant interest in pharmaceutical research and development. This modified nucleoside serves as a critical building block and a key intermediate in the synthesis of novel antiviral and anticancer agents. It is primarily utilized by research institutions, pharmaceutical companies, and biotechnology firms engaged in medicinal chemistry and drug discovery programs. The compound's unique structure allows for the exploration of mechanisms involving DNA/RNA synthesis inhibition.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Medicinal Chemistry Research: Used as a building block for structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Biochemical Research: Employed in enzymatic studies to investigate substrate specificity and inhibition mechanisms.
• Antiviral Drug Development: Investigated for its potential activity against viral polymerases.
• Oncology Research: Studied for its incorporation into DNA and potential cytotoxic effects on rapidly dividing cells.
• Labeled Compound Synthesis: Serves as a starting material for the preparation of isotopically labeled (e.g., tritiated) compounds for tracer studies.

Basic Information

Product Name	2-Fluoro-3'-Deoxyadenosine
CAS No.	15386-69-3
Molecular Formula	C10H12FN5O3
Molecular Weight	269.23 g/mol
Synonyms	2-Fluoro-2',3'-dideoxyadenosine; 2-Fluoro-ddA; 9-(2,3-Dideoxy-β-D-erythro-pentofuranosyl)-2-fluoroadenine; 2-F-2',3'-ddA; 2-Fluoro-2',3'-dideoxyadenosine; 2-Fluorodideoxyadenosine; 2-Fluoro-3'-deoxyadenosine; 2-Fluoro-2',3'-dideoxyadenosine (2-F-ddA)
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3'-Deoxyadenosine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.