Description

(5B,12B)- 12-Hydroxycholan-24-Oic Acid is a specific hydroxylated derivative of cholanic acid, a key structural motif in bile acid chemistry. This compound serves as a valuable pharmaceutical intermediate and research chemical for the synthesis of more complex steroid-based molecules. It is primarily utilized by pharmaceutical R&D departments, academic research institutions, and manufacturers of fine chemicals and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel steroid-based therapeutics and bile acid derivatives.
• Biochemical Research: Used as a standard or reagent in studies investigating bile acid metabolism, receptor interactions, and signaling pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Fine Chemical Synthesis: Employed in the production of specialized chiral compounds and complex molecular architectures for various research applications.
• Metabolic Pathway Studies: Utilized in research to understand the role of specific bile acid analogs in biological systems.

Basic Information

Product Name	(5B,12B)- 12-Hydroxycholan-24-Oic Acid
CAS No.	15173-23-6
Molecular Formula	C24H40O4
Molecular Weight	392.57 g/mol
Synonyms	12α-Hydroxycholanic Acid; 12α-Hydroxy-5β-cholan-24-oic Acid; 12-Hydroxy-5β-cholan-24-oic Acid; 3α,7α,12α-Trihydroxy-5β-cholan-24-oic Acid (Note: This is a common related trihydroxy acid; verify structure); 5β-Cholan-24-oic acid, 12α-hydroxy-; 12-Hydroxycholanic Acid
EINECS	Contact for details

Quality Control

Our (5B,12B)- 12-Hydroxycholan-24-Oic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and synthesis. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). This compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.