Description

(3B,5A,7A,12A)-3,7,12-Trihydroxy-Cholan-24-Oic Acid is a key bile acid derivative and an important biochemical intermediate. This compound is valued for its role as a precursor in the synthesis of more complex bile acids and pharmaceutical agents. It is primarily required by manufacturers in the pharmaceutical, research, and fine chemical sectors for applications in drug development and metabolic studies.

Application

• Pharmaceutical Intermediate: A critical starting material or intermediate in the synthesis of therapeutic bile acids and related steroid-based pharmaceuticals.
• Biochemical Research: Used as a standard or reagent in metabolic pathway studies, hepatology research, and investigations into cholesterol metabolism.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Fine Chemical Synthesis: Employed in organic synthesis to introduce the characteristic trihydroxy cholanic acid structure into more complex molecules.
• Digestive Aid Research: Investigated for potential applications in formulations related to lipid digestion and absorption.

Basic Information

Product Name	(3B,5A,7A,12A)-3,7,12-Trihydroxy-Cholan-24-Oic Acid
CAS No.	15073-87-7
Molecular Formula	C24H40O5
Molecular Weight	408.57 g/mol
Synonyms	3α,7α,12α-Trihydroxy-5β-cholan-24-oic Acid; Cholic Acid Impurity; Trihydroxycholanic Acid; 5β-Cholan-24-oic Acid-3α,7α,12α-triol; 3α,7α,12α-Trihydroxy-5β-cholanic Acid; Cholanoic Acid Derivative; 7α,12α-Dihydroxy-3-oxo-5β-cholan-24-oic Acid (related); Hyocholic Acid (isomer)
EINECS	Contact for details

Quality Control

Our (3B,5A,7A,12A)-3,7,12-Trihydroxy-Cholan-24-Oic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical and research applications. Certificates of Analysis (COA) documenting all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Specific Optical Rotation	Contact for details
Heavy Metals	< 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.