Description

N(3)-Benzyluridine is a chemically modified nucleoside derivative, specifically a uridine analog with a benzyl group at the N3 position. This modification is crucial for imparting unique biochemical properties, making it a valuable intermediate in advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents, particularly in the fields of antiviral drug discovery and oligonucleotide chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel nucleoside-based antiviral and anticancer prodrugs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to understand polymerase and transferase mechanisms.
• Oligonucleotide Synthesis: Serves as a modified monomer for incorporating specific functionalities into DNA or RNA strands for diagnostic and therapeutic applications.
• Proteomics & Genomics: Employed in the development of probes and tools for studying nucleic acid-protein interactions and cellular processes.
• Medicinal Chemistry: A versatile scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Academic Research: Fundamental research tool in universities and institutes for exploring nucleic acid chemistry and biochemistry.

Basic Information

Product Name	N(3)-Benzyluridine
CAS No.	14985-34-3
Molecular Formula	C₁₆H₁₈N₂O₆
Molecular Weight	334.32 g/mol
Synonyms	3-Benzyluridine; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3-benzylpyrimidine-2,4(1H,3H)-dione; N3-Benzyluridine; Uridine, 3-benzyl-; 3-Benzyl-1-β-D-ribofuranosyluracil
EINECS	Contact for details

Quality Control

Our N(3)-Benzyluridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets high-purity research-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.