Description

4-Azidobenzoyl Chloride is a versatile and highly reactive aromatic acid chloride derivative, primarily valued for its azide functional group which enables efficient click chemistry and photoaffinity labeling. This compound is essential for researchers and manufacturers requiring precise, covalent modification of biomolecules and polymers under mild conditions. It is a critical intermediate for pharmaceutical R&D, materials science, and the synthesis of advanced probes and polymers.

Application

• Photoaffinity Labeling Probes: Used to create covalent bonds with biological targets upon UV irradiation for studying protein-ligand interactions and drug discovery.
• Click Chemistry Reagent: Serves as a key building block in Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for bioconjugation and polymer functionalization.
• Polymer Modification: Employed to introduce azide groups into polymer backbones or surfaces for subsequent cross-linking or grafting of functional molecules.
• Pharmaceutical Intermediate: A crucial synthon in the synthesis of novel active pharmaceutical ingredients (APIs) and diagnostic agents.
• Surface Functionalization: Used to modify material surfaces (e.g., gold, silicon) with azide-terminated monolayers for sensor development and biomaterial engineering.
• Cross-linking Agent: Facilitates the formation of stable networks in hydrogel and polymer matrix development.

Basic Information

Product Name	4-Azidobenzoyl Chloride
CAS No.	14848-01-2
Molecular Formula	C7H4ClN3O
Molecular Weight	181.58 g/mol
Synonyms	p-Azidobenzoyl Chloride; 4-Azidobenzoic Acid Chloride; Azidobenzoyl Chloride; Benzoic acid, 4-azido-, chloride; 4-Azidobenzoyl chloride; 14848-01-2; p-Azidobenzoyl chloride; 4-Azidobenzoylchloride
EINECS	Contact for details

Quality Control

Our 4-Azidobenzoyl Chloride is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at temperatures between 2°C and 8°C (refrigerated) to maintain stability due to its light-sensitive and hygroscopic nature. Keep away from heat, open flames, and incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Standard Grade)
Melting Point	Contact for details
Water Content (KF)	< 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.