Description

5α-Pregnan-3-One CAS NO 14778-11-1 is a high-purity steroid intermediate, specifically a 5α-reduced pregnane derivative, essential for advanced pharmaceutical synthesis and biochemical research. This compound serves as a critical building block for the development of neurosteroids and other biologically active molecules targeting the central nervous system. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions focused on endocrinology and neuropharmacology.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of neuroactive steroids like allopregnanolone and related analogs.
• Biochemical Research: Used as a reference standard and starting material for studying GABA-A receptor modulation and neurosteroid pathways.
• Fine Chemical Synthesis: Serves as a versatile scaffold for the preparation of more complex steroid-based active pharmaceutical ingredients (APIs).
• Reference Standard: Employed in analytical laboratories for method development, calibration, and quality control of steroid-based products.
• Metabolite Studies: Utilized in metabolic and pharmacokinetic research related to endogenous steroid hormones.

Basic Information

Product Name	5α-Pregnan-3-One
CAS No.	14778-11-1
Molecular Formula	C21H34O
Molecular Weight	302.50 g/mol
Synonyms	5α-Pregnan-3-one; 3-Oxo-5α-pregnane; Dihydroprogesterone (5α); 5α-DHP; 5α-Pregnane-3,20-dione (common misnomer); NSC 11336; 5α-Pregnane-3-one; Allopregnanone precursor
EINECS	Contact for details

Quality Control

Our 5α-Pregnan-3-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all test results is provided to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.