Description

3-Oxo-7α-Hydroxy-5α-Cholanic Acid Methyl Ester is a high-purity steroidal intermediate of significant importance in advanced pharmaceutical synthesis. This compound serves as a critical building block for the production of specialized bile acids and other bioactive steroid derivatives. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents and fine chemical processes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex steroid-based active pharmaceutical ingredients (APIs).
• Bile Acid Research: Used as a starting material or reference standard in the study of bile acid metabolism and related biochemical pathways.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to introduce specific steroidal frameworks into target molecules.
• Biochemical Research: Utilized in laboratory settings to investigate steroid hormone interactions and receptor binding studies.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	3-Oxo-7α-Hydroxy-5α-Cholanic Acid Methyl Ester
CAS No.	14772-96-4
Molecular Formula	C₂₅H₄₀O₄
Molecular Weight	404.59 g/mol
Synonyms	7α-Hydroxy-3-oxo-5α-cholan-24-oic Acid Methyl Ester; Methyl 7α-Hydroxy-3-oxo-5α-cholan-24-oate; 3-Keto-7α-hydroxy-5α-cholanic Acid Methyl Ester; Methyl 3-Keto-7α-hydroxy-5α-cholanate; 5α-Cholan-24-oic Acid, 7α-Hydroxy-3-oxo-, Methyl Ester; Methyl 7α-Hydroxy-3-oxolithocholate
EINECS	Contact for details

Quality Control

Our 3-Oxo-7α-Hydroxy-5α-Cholanic Acid Methyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by spectroscopic methods, to ensure it meets the stringent requirements for research and synthesis. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Specified range
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.