Description

2,5-Dichloro-4-(2-Iodoacetylamino)Phenyl Thiocyanate is a specialized halogenated aromatic compound that serves as a versatile synthetic intermediate. Its unique structure, featuring reactive chloro, iodoacetyl, and thiocyanate functional groups, makes it a valuable building block for constructing complex molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme inhibition or receptor modulation.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated aromatic core for bioactivity.
• Chemical Biology Probe Synthesis: Serves as a starting material for creating affinity probes or photoaffinity labels due to the reactive iodoacetyl group for bioconjugation.
• Material Science Research: Intermediate for synthesizing specialized polymers or liquid crystals where the thiocyanate and halogen groups influence material properties.
• Cross-coupling Reactions: Substrate for palladium-catalyzed reactions (e.g., Suzuki, Sonogashira) where the chlorine atoms act as leaving groups.
• Heterocyclic Compound Synthesis: Building block for constructing complex nitrogen- and sulfur-containing heterocycles, important scaffolds in medicinal chemistry.

Basic Information

Product Name	2,5-Dichloro-4-(2-Iodoacetylamino)Phenyl Thiocyanate
CAS No.	14664-96-1
Molecular Formula	C9H5Cl2IN2OS
Molecular Weight	399.02 g/mol
Synonyms	N-(4-Thiocyanato-2,5-dichlorophenyl)-2-iodoacetamide; 2-Iodo-N-(2,5-dichloro-4-thiocyanatophenyl)acetamide; 2,5-Dichloro-4-thiocyanatoaniline iodoacetamide derivative; 4-Amino-2,5-dichlorophenyl thiocyanate iodoacetamide; 14664-96-1; 2,5-Dichloro-4-isothiocyanatoaniline iodoacetamide; Acetamide, 2-iodo-N-(2,5-dichloro-4-thiocyanatophenyl)-
EINECS	Contact for details

Quality Control

Our 2,5-Dichloro-4-(2-Iodoacetylamino)Phenyl Thiocyanate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliable and traceable material for critical synthetic pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.