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Uridine 5'-(Trihydrogen Diphosphate), Mono-α-D-Glucopyranosyl Ester, Sodium Salt CAS NO 14656-80-5


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CAS No.:14656-80-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Uridine 5'-(Trihydrogen Diphosphate), Mono-α-D-Glucopyranosyl Ester, Sodium Salt is a nucleotide sugar derivative that serves as a key biochemical intermediate in glycosylation pathways. This compound is critical for researchers and manufacturers requiring a high-purity, stable form of UDP-glucose for enzymatic synthesis and metabolic studies. It is primarily utilized in the pharmaceutical, biotechnology, and life science research sectors for applications ranging from drug discovery to the synthesis of complex carbohydrates and glycoconjugates.

Application

  • Enzymatic Synthesis Substrate: Acts as a glucosyl donor in the enzymatic synthesis of oligosaccharides, glycoproteins, and glycolipids.
  • Biochemical Research: Used as a critical reagent in studies of glycosyltransferase enzymes, carbohydrate metabolism, and cell signaling pathways.
  • Pharmaceutical Intermediates: Serves as a building block in the research and development of nucleotide-based therapeutics and prodrugs.
  • Diagnostic Kit Manufacturing: Incorporated into diagnostic assays and kits that measure enzymatic activity related to glycogen storage diseases or other metabolic disorders.
  • Cell Culture & Media Supplement: Used in specialized cell culture media to support the glycosylation processes in recombinant protein production.
  • Glycoengineering: Essential for in vitro glycoengineering efforts aimed at creating defined glycan structures on therapeutic proteins.

Basic Information

Product Name Uridine 5'-(Trihydrogen Diphosphate), Mono-α-D-Glucopyranosyl Ester, Sodium Salt
CAS No. 14656-80-5
Molecular Formula C15H23N2NaO17P2
Molecular Weight 610.27 g/mol
Synonyms UDP-Glucose Sodium Salt; Uridine Diphosphate Glucose Sodium Salt; UDP-Glc Sodium; UDP-α-D-Glucose Sodium Salt; Uridine 5'-(α-D-Glucopyranosyl Diphosphate) Sodium Salt; UDPG Sodium Salt; 5'-Uridylic Acid, Mono-α-D-glucopyranosyl Ester, Sodium Salt
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Quality Control

Our Uridine 5'-(Trihydrogen Diphosphate), Mono-α-D-Glucopyranosyl Ester, Sodium Salt is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and manufacturing. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the container to reach room temperature before opening to minimize condensation and moisture uptake.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC/UV) Conforms
Purity (HPLC) ≥ 95%
Assay ≥ 90% (UDP-Glucose basis)
Water Content (KF) ≤ 5.0%
pH (1% Solution) 6.0 - 8.0
Biological Activity Conforms (Enzymatic Test)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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