Description

n-Benzyl-n-Ethyltrimethylsilylamine is a highly reactive organosilicon compound, specifically a silylated secondary amine. This chemical is valued for its dual functionality as a strong, non-nucleophilic base and as a versatile silylating agent in advanced organic synthesis. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the protection of sensitive functional groups and the facilitation of challenging bond-forming reactions.

Application

• Pharmaceutical Intermediate Synthesis: Employed as a key reagent in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly for deprotonation and silylation steps.
• Protecting Group Chemistry: Used to introduce the trimethylsilyl (TMS) group, protecting alcohols, amines, and other nucleophiles during complex synthetic sequences.
• Base-Catalyzed Reactions: Acts as a strong, sterically hindered base to generate reactive enolates and other carbanions in condensation and alkylation reactions.
• Agrochemical Manufacturing: Serves as a building block in the production of advanced herbicides, fungicides, and plant growth regulators.
• Material Science Precursor: Utilized in the synthesis of silicon-containing polymers, dendrimers, and surface-modifying agents.
• Laboratory Reagent: A valuable tool in academic and industrial R&D for methodological development and the synthesis of novel organic molecules.

Basic Information

Product Name	n-Benzyl-n-Ethyltrimethylsilylamine
CAS No.	14629-66-4
Molecular Formula	C₁₂H₂₁NSi
Molecular Weight	207.39 g/mol
Synonyms	N-Benzyl-N-ethyltrimethylsilylamine; N-Ethyl-N-(trimethylsilyl)benzylamine; Benzyl(ethyl)trimethylsilylamine; (Benzylethylamino)trimethylsilane; Ethyl(benzyl)trimethylsilylamine; BnNEtTMSA; TMS-BnNEt
EINECS	Contact for details

Quality Control

Our n-Benzyl-n-Ethyltrimethylsilylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated area. Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed and allowed to reach room temperature before opening to minimize moisture ingress and loss of product.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.