Description

n-(α-Methylphenethyl)Trimethylsilylamine is a specialized organosilicon amine compound, serving as a versatile building block and protecting group reagent in advanced organic synthesis. Its value lies in its ability to introduce the trimethylsilyl (TMS) group and modify amine functionalities under controlled conditions, enabling the synthesis of complex molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Amino Group Protection: Acts as a silylating agent to protect primary and secondary amine groups during complex synthetic sequences.
• Fine Chemical Synthesis: Used in the research and production of specialty chemicals, agrochemicals, and advanced materials.
• Catalyst and Ligand Preparation: Serves as a precursor for modifying catalysts and creating novel ligands in organometallic chemistry.
• Academic and R&D Laboratories: A valuable reagent for methodological development and exploratory organic synthesis in research institutions.

Basic Information

Product Name	n-(α-Methylphenethyl)Trimethylsilylamine
CAS No.	14629-65-3
Molecular Formula	C₁₂H₂₁NSi
Molecular Weight	207.39 g/mol
Synonyms	N-[(1S)-1-Phenylethyl]-1,1,1-trimethylsilanamine; N-(1-Phenylethyl)trimethylsilylamine; (S)-N-(1-Phenylethyl)trimethylsilylamine; Trimethyl[(1-phenylethyl)amino]silane; N-Trimethylsilyl-α-methylbenzylamine; α-Methylbenzyltrimethylsilylamine; (α-Methylphenethyl)trimethylsilylamine
EINECS	Contact for details

Quality Control

Our n-(α-Methylphenethyl)Trimethylsilylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.