Description

(4-Methoxybenzyl)(Trimethylsilyl) Ether is a versatile organosilicon protecting group reagent, specifically designed for the selective protection of alcohols and phenols in complex organic synthesis. Its core value lies in its stability under a wide range of reaction conditions and its orthogonal deprotection profile, enabling precise synthetic control. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require high-purity intermediates for multi-step synthesis.

Application

• Pharmaceutical Intermediate Synthesis: Used as a protecting group for hydroxyl functionalities during the multi-step synthesis of active pharmaceutical ingredients (APIs) and complex natural products.
• Agrochemical Manufacturing: Employed in the production of advanced pesticides and herbicides where selective protection/deprotection sequences are required.
• Peptide & Oligonucleotide Chemistry: Facilitates the synthesis of sensitive biomolecules by protecting specific sites from unwanted side reactions.
• Fine Chemical Production: Serves as a key reagent in the manufacture of specialty chemicals, flavors, and fragrances requiring precise molecular architecture.
• Academic & Industrial R&D: A critical tool in research laboratories for method development and exploring new synthetic pathways in organic chemistry.
• Material Science: Used in the surface modification of silicates and the synthesis of silicon-containing polymers and advanced materials.

Basic Information

Product Name	(4-Methoxybenzyl)(Trimethylsilyl) Ether
CAS No.	14629-56-2
Molecular Formula	C11H18O2Si
Molecular Weight	210.35 g/mol
Synonyms	PMB-OTMS; 4-Methoxybenzyl Trimethylsilyl Ether; 1-[(Trimethylsilyl)oxy]methyl-4-methoxybenzene; p-Methoxybenzyl Trimethylsilyl Ether; (4-Methoxybenzyl)oxytrimethylsilane; (p-Methoxybenzyloxy)trimethylsilane; Trimethyl[(4-methoxybenzyl)oxy]silane; MPM-OTMS
EINECS	Contact for details

Quality Control

Our (4-Methoxybenzyl)(Trimethylsilyl) Ether is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.