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2'-Deoxyguanosine-5'-Monophosphate Ammonium Salt CAS NO 14543-77-2
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CAS No.:14543-77-2
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2'-Deoxyguanosine-5'-Monophosphate Ammonium Salt is a high-purity nucleotide derivative, essential for biochemical research and pharmaceutical development. Its primary value lies in its role as a critical building block for oligonucleotide synthesis, DNA sequencing, and as a reference standard. This product is vital for biotechnology companies, diagnostic manufacturers, and academic research institutions focused on molecular biology, genomics, and therapeutic nucleic acid development.
Application
- Oligonucleotide Synthesis: A key monomer (dGMP) in the solid-phase synthesis of DNA strands for PCR primers, probes, and antisense oligonucleotides.
- Pharmaceutical Research: Used in the development and manufacturing of nucleotide-based therapeutics, including aptamers and antisense drugs.
- Diagnostic Reagents: Serves as a component in kits for DNA labeling, sequencing, and various molecular diagnostic assays.
- Biochemical Research: Employed as a substrate for enzymes like kinases and polymerases in enzymatic studies and metabolic pathway analysis.
- Reference Standard: Used for calibration, method development, and quality control in analytical laboratories (HPLC, MS).
- Cell Culture & Media: Can be utilized as a nutrient supplement in specialized cell culture media formulations.
Basic Information
| Product Name | 2'-Deoxyguanosine-5'-Monophosphate Ammonium Salt |
| CAS No. | 14543-77-2 |
| Molecular Formula | C10H17N6O7P • xNH3 |
| Molecular Weight | Contact for details |
| Synonyms | Deoxyguanylic Acid Ammonium Salt; dGMP Ammonium Salt; 2'-Deoxy-GMP Ammonium Salt; Guanosine 5'-(dihydrogen phosphate) 2'-deoxy-, ammonium salt; 2'-Deoxyguanosine 5'-monophosphate ammonium; Deoxyguanosine monophosphate ammonium salt; dG-NH4 |
| EINECS | Contact for details |
Quality Control
Every batch of 2'-Deoxyguanosine-5'-Monophosphate Ammonium Salt is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the product meets the stringent requirements for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and must be kept under desiccated conditions. Allow the sealed container to reach room temperature before opening to prevent condensation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (HPLC) | Conforms to reference standard |
| Identification (IR) | Conforms to structure |
| Assay (HPLC) | ≥ 98.0% |
| Water Content (KF) | ≤ 5.0% |
| pH (1% Solution) | 6.5 - 7.5 |
| Related Substances (HPLC) | Total impurities ≤ 2.0% |
| Solubility | Soluble in water |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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