Description

3β,14-Dihydroxy-19-Oxocarda-4,20(22)-Dienolide is a specialized cardenolide derivative, a class of compounds known for their potent biological activity. This high-purity intermediate is critical for pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents targeting cardiovascular functions. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and advanced chemical synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel cardiotonic steroids and other bioactive molecules.
• Biochemical Research: Used as a reference standard or probe in studies investigating sodium-potassium ATPase (Na+/K+-ATPase) inhibition and related cellular signaling pathways.
• Medicinal Chemistry: Serves as a core scaffold for the structural modification and development of new chemical entities with potential therapeutic applications.
• Academic Research: Employed in university and institutional labs for pharmacological and toxicological studies related to cardiac glycosides.

Basic Information

Product Name	3β,14-Dihydroxy-19-Oxocarda-4,20(22)-Dienolide
CAS No.	14530-91-7
Molecular Formula	C₂₃H₃₂O₅
Molecular Weight	388.50 g/mol
Synonyms	19-Oxocarda-4,20(22)-dienolide-3β,14-diol; 3β,14-Dihydroxy-19-oxocarda-4,20(22)-dienolide; 19-Oxobufalin; 3β,14-Dihydroxy-19-oxobufa-4,20,22-trienolide; Bufa-4,20,22-trienolide, 3,14-dihydroxy-19-oxo-, (3β)-; 19-Oxobufa-4,20,22-trienolide-3β,14-diol
EINECS	Contact for details

Quality Control

Our 3β,14-Dihydroxy-19-Oxocarda-4,20(22)-Dienolide is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container sealed to protect the product from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.