Description

1H-Benzimidazole, 1-Ribofuranosyl- is a nucleoside analog that combines a benzimidazole base with a ribose sugar moiety. This molecular structure makes it a valuable intermediate in the synthesis of novel antiviral and pharmaceutical compounds, particularly those targeting RNA-based mechanisms. It is primarily utilized by research institutions and pharmaceutical development companies engaged in nucleoside chemistry and medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: Key building block in the research and development of antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies involving nucleoside-processing enzymes.
• Medicinal Chemistry: Serves as a core scaffold for the design and synthesis of new chemical entities with potential therapeutic activity.
• Nucleoside Chemistry: Fundamental reagent for studying structure-activity relationships (SAR) in modified nucleosides.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	1H-Benzimidazole, 1-Ribofuranosyl-
CAS No.	14505-70-5
Molecular Formula	C₁₂H₁₄N₂O₄
Molecular Weight	250.25 g/mol
Synonyms	1-(β-D-Ribofuranosyl)benzimidazole; 1-Ribofuranosylbenzimidazole; 1-(β-D-Ribofuranosyl)-1H-benzimidazole; NSC 401005; Benzimidazole riboside; 1H-Benzimidazole, 1-β-D-ribofuranosyl-; 1-β-D-Ribofuranosyl-1H-benzimidazole
EINECS	Contact for details

Quality Control

Our 1H-Benzimidazole, 1-Ribofuranosyl- is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR for structural confirmation, and residual solvent analysis to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.