Description

4-Morpholineglyoxyloyl Chloride (8Ci) is a highly reactive acid chloride derivative of morpholine, serving as a critical acylating and building block agent in advanced organic synthesis. Its value lies in enabling the efficient introduction of the morpholineglyoxyloyl moiety, a key structural feature in the development of pharmacologically active molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new drugs, agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the morpholine ring enhances biological activity.
• Peptide Mimetics & Bioactive Molecule Development: Employed as an acylating agent to create peptide analogs and other complex bioactive compounds for research.
• Ligand & Catalyst Preparation: Acts as a precursor for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis.
• Polymer Chemistry: Can be utilized in the modification of polymers to introduce specific functional groups, altering material properties.
• Chemical Research & Development: Serves as a versatile reagent in academic and industrial R&D for exploring new synthetic pathways and molecular architectures.

Basic Information

Product Name	4-Morpholineglyoxyloyl Chloride (8Ci)
CAS No.	14505-42-1
Molecular Formula	C6H8ClNO3
Molecular Weight	177.59 g/mol
Synonyms	4-Morpholineglyoxylic Acid Chloride; Morpholine-4-glyoxyloyl Chloride; 2-Chloro-2-oxo-1-(morpholin-4-yl)ethanone; 4-(Chlorooxoacetyl)morpholine; 4-Morpholinecarbonyl Chloride, Oxo-; (Morpholino)oxoacetyl Chloride; 8Ci (Code for specific isomeric form); Glyoxylic Acid Chloride, 4-Morpholino-
EINECS	Contact for details

Quality Control

Our 4-Morpholineglyoxyloyl Chloride is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at temperatures between 2°C and 8°C (refrigerated) to maintain stability and minimize degradation due to its hygroscopic and highly volatile nature. Keep away from strong bases, oxidizing agents, and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.